The antiviral drug Paxlovid works by combining nirmatrelvir and ritonavir to block SARS-CoV-2’s main... View more
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The antiviral drug Paxlovid works by combining nirmatrelvir and ritonavir to block SARS-CoV-2’s main protease and stop viral replication. Ritonavir functions as a metabolic inhibitor, which reduces the breakdown speed of nirmatrelvir, thus extending its antiviral effects. Paxlovid is delivered through oral administration and intended for patients aged 12 years or older who have mild-to-moderate COVID-19 but face potential progression to severe illness.